Is there anything I can do..... looks like fatality number 3 is imminent

Well Bumble (the sick Hen) is currently at the vet with my husband. I don't think she will be coming home again. We have discussed the cost of a post mortem when we made the appointment and they said £15, so if there is nothing that can be done for her, then she will have a pm to try and find out if this mystery can be solved.

Will keep you posted.

Truly sorry, I do hope you find the cause.xxx

Thanks for letting us know the results and sorry it turned out so badly for the orps.

When I read colernehens first post I had my suspictions which is why I asked about the milky droppings or green in advanced cases of LL.  The timing of the deaths was also very typical of LL 16 to 18 weeks incubation is usual.  However I don't like to jump to such a grim diagnosis when a toxin could also produce these symptoms but the second post more or less ruled that out.  I've come across this before and it's more widespread than is generally reported as it's often misdiagnosed as Mareks.

You may get some joy from going back to the breeder with your vets report it depends on how reputable (s)he is.  Anyone reading this if you are buying stock from a breeder never be affraid to ask about health issues and how they ensure heathy stock and what guarentee they will give should a bird develop an illness which is clearly linked to it's breeding.  Here LL could only have come from an infected parent bird.  You can always ask about vaccination but many smaller breeders won't vaccinate anyway.  There no vaccine for LL anyway.

Your remaining Orp could be carrying the virus or not it doesn't always produce tumours or prove fatal.  

LL is passed vertically usually via the egg so the offspring of an infected parent will be infected.  So obviously you shouldn't breed from this hen.  The virus isn't very contagious and is easily killed with good sanitation and exposure to a disinfectant.  Horizontal infection isn't as virulent as vertical as adult birds have some immunity but LL infected hens don't pass on antibodies to the egg.

So I'd suggest if you want to take the small risk this bird might transmit the disease horizontally you could keep her.  Clean up as best you can and disinfect the house and run using Vanodine V18 spray or Stalosan F powder disinfectant.  Keep this bird away from young chicks and keep an eye out for symptoms particularly milky droppings.  Cull if she shows symptoms of the disease but she maybe lucky.

Best of luck
HF

at least with the post mortem you will have the proof to confront him.
Sadly this is all too familiar - Grumpy dad lost a lot of hens to Mareks (confirmed after a pm) from a bad breeder who never acknowledged he had injected them with old vaccine (mareks vaccine needs to be used within an hour of opening it) and I lost 7 chicks to vent gleet through a breeder either hatching dirty infected eggs or not cleaning his incubator properly again proven by a pm (they were too young to get it off a cockerel and my feed is kept dry and mould free).