I would say beware of the raspberries. we bought some, short of somewhere to put them we potted them and 'plunged' them on the poly. the roots escaped and they are everywhere, because it's dryer in there presumably they are searching for more moisture. lovely clean rasps though, completely protected form the birds
I would think your comfrey can always be dug out in the future, if it keeps coming up unwanted then put some weed fabric down and keep pots of things on it?
Our poly should be 30ft, but we shortened the distance between the hoops for extra strength, so it's 25ft, well concreted in, esp at the corners!
If you are puttng it up yourself make sure the plastic is TIGHT. our first cover, rated 4 years lasted over 10, we had someone in to do the cover. The one we put on flaps about a little and I can tell it isn't going to last as long, bits of tears already